Publications:

PUBLISHED WORK:

  1. Davoudi S, Chin C-Y, Cooke MC, Tam RY, Shoichet MS, and Gilbert PM. (2018) Muscle stem cell intramuscular delivery within hyaluronin methylcellulose improves engraftment efficiency and dispersion. Biomaterials, 173: 34-46.

  2. Li EW, McKee-Muir OC, and Gilbert PM. (2018) Cellular biomechanics in skeletal muscle regeneration. Myogenesis in Development and Disease, Sassoon D (Ed.) Amsterdam, Netherlands: Elsevier, In Press.

  3. Safaee H, Bakooshli MA, Davoudi S, Cheng RY, Martowirogo AJ, Li EW, Simmons CA, and Gilbert PM. (2017) Tethered Jagged-1 synergizes with culture substrate stiffness to modulate Notch-induced myogenic progenitor differentiation. Cellular and Molecular Bioengineering, 10(5): 501-513.

  4. Davoudi S and Gilbert PM. (2017) Optimization of satellite cell culture through biomaterials. Methods in Molecular Biology, E. Perdiguero and D. Cornelison (ed.), New York, NY: Springer, 1556: 329-341.

  5. Gilbert PM* and Weaver VM*. (*Co-corresponding authors; 2016) Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Seminars in Cell and Developmental Biology, 67: 141-152.

  6. Nissar A, Martowirogo A, and Gilbert PM. (2016) Targeting the stem cell niche with regenerative biomaterials. Current Opinion in Solid State and Materials Science, 20(4): 180-192.

  7. Morrissey-Scoot JD, Cheng R, Davoudi S, and Gilbert PM. (2016) Biomechanical origins of muscle stem cell signal transduction. J. Molecular Biology, 428(7): 1441-54.

  8. Gomez-Aristizabal A, Sharma A, Bakooshli MA, Kapoor M, Gilbert PM, Viswanathan S, and Gandhi R. (2016) Stage-specific differences in secretory profile of mesenchymal stromal cells subjected to early- vs late- OA synovial fluid. Osteoarthritis and Cartilage, 5: 737-741.

  9. Bakooshli MA and Gilbert PM. (2015) Muscling in on the third dimension. eLIFE, DOI: 10.7554/eLife.06430

  10. Magnusson KEG, Jalden J, Gilbert PM, and Blau HM. (2015) Global linking of tracks using Viterbi algorithm. IEEE Transactions on Medical Imaging, 34(4): 911-929.

  11. Cosgrove BD, Gilbert PM*, Porpiglia E, Mourkioti F, Lee SP, Corbel SY, Llewellyn ME, Delp SP and Blau HM*. (*Co-corresponding authors; 2014) Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. Nature Medicine, 20:255-64.

  12. Mouw JK, Yui Y, Damiano L, O Bainer R, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen Y-Y and Weaver VM. (2014) Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nature Medicine, 20:360-367.

  13. Gilbert PM, Corbel S, Doyonnas R, Havenstrite K, Magnusson K.E.G. and Blau HM. (2012) A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. Integrative Biology, 360-367.

  14. Sengupta D, Gilbert PM, Johnson KL, Blau HM and Heilshorn SC (2012) Protein-engineered biomaterials to generate human skeletal muscle mimics. Advanced Healthcare Materials, 1(6):785-789.

  15. Gibbs KD Jr., Gilbert PM, Blau HM, Weissman IL, Nolan GP, and Majeti R (2011) Single cell analysis of phosphor-signaling networks reveals G-SCF drives human hematopoietic stem cells into cell cycle. Blood, 117(16):4226-33.

  16. Gilbert PM and Blau HM. (2011) Engineering a stem cell house into a home. Stem cell research and therapy, 2(1): 1-9.

  17. Gilbert PM*, Havenstrite K*, Magnusson KEG, Sacco A, Leonardi N, Nguyen N, Kraft P, Thrun S, Lutolf M and Blau HM. (*Equal Contribution; 2010) Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science, 329(5995): 1078-81.

  18. Gilbert PM*, Mouw JK*, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KKC., Welm AL, Feldman MD, Weber BL, and Weaver VM (*Equal contribution; 2010) HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. Journal of Clinical Investigation, 120(5):1535-50.

  19. Lutolf M, Gilbert PM and Blau HM (2009) Designing biomaterials to direct stem cell fate. Nature, 462:  433-441.

  20. Blau HM, Sacco A, and Gilbert PM (2009) Skeletal muscle stem cells. Essentials of Stem Cell Biology.  R. Lanza et al (Eds.) San Diego, California: Academic Press Inc: 249-257.

  21. Cosgrove BD, Sacco A, Gilbert PM, Blau HM (2009) A home away from home: Challenges and opportunities in engineering in vitro muscle satellite cell niches. Differentiation, 78(203):  185-94.

  22. Blau HM, Sacco A, and Gilbert PM. (2008) Stem cell self-renewal. Stem Cell Encyclopedia.  SAGE Publishing.

  23. Geng J, Shin ME, Gilbert PM, Collins RN, and Burd CG (2005) Saccharomyces cerevisiae Rab-GDI displacement factor ortholog Yip3p forms distinct complexes with the Ypt1 Rab GTPase and the reticulon Rtn1p. Eukaryotic Cell, Jul 4(7): 1166-1174.

  24. Weaver VM and Gilbert P (2004) Watch thy neighbor: cancer is a communal affair. Journal of Cell Science, 117(Pt8): 1287-1290.

  25. Calero M, Chen CZ, Zhu W, Winand N, Havas KA, Gilbert PM, Burd CG, and Collins RN (2003) Dual prenylation is required for Rab protein localization and function. Molecular Biology of the Cell, 14(5): 1852-1867.

  26. Shin ME, Ogburn KD, Varban OA, Gilbert PM, and Burd CG (2001) FYVE domain targets Pib1 ubiquitin ligase to endosome and vacuolar membranes. Journal of Biological Chemistry, 276(44): 41388-41393.

  27. Gilbert PM and Burd CG (2001) GDP dissociation inhibitor domain II required for Rab GTPase recycling. Journal of Biological Chemistry, 267(11): 8014-8020.

  28. Nixon, Allison M. L., et al. “A Rapid in Vitro Methodology for Simultaneous Target Discovery and Antibody Generation against Functional Cell Subpopulations.” Scientific Reports, vol. 9, no. 1, 2019, doi:10.1038/s41598-018-37462-1.

  29. Bakooshli, Mohsen Afshar, et al. “A Three-Dimensional Culture Model of Innervated Human Skeletal Muscle Enables Studies of the Adult Neuromuscular Junction and Disease Modeling.” 2018, doi:10.1101/275545.

PREPRINTS:

  1. Davoudi S, Chin C-Y, Mumtaz A, Cooke MC, Tam RY, Shoichet MS, and Gilbert PM (2018). Muscle stem cell intramuscular delivery within hyaluronin methylcellulose improves engraftment efficiency and dispersion. BioRxiv, https://doi.org/10.1101/245258.

  2. Bakooshli MA, Lippman ES, Mulcahy B, Iyer N, Nguyen CT, Tung K, Stewart BA, van den Dorpel H, Fuehrmann T, Shoichet MS, Bigot A, Pegoraro E, Ahn H, Ginsberg H, Zhen M, Ashton RS, and *Gilbert PM (2018). A three-dimensional culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction and disease modeling. BioRxiv, https://doi.org/10.1101/275545.

MECHANOBIOLOGY PUBLICATIONS:

  1. Li EW, McKee-Muir OC, and Gilbert PM. (2018) Cellular biomechanics in skeletal muscle regeneration. Myogenesis in Development and Disease, Sassoon D (Ed.) Amsterdam, Netherlands: Elsevier, In Press.

  2. Safaee H, Bakooshli MA, Davoudi S, Cheng RY, Martowirogo AJ, Li EW, Simmons CA, and Gilbert PM. (2017) Tethered Jagged-1 synergizes with culture substrate stiffness to modulate Notch-induced myogenic progenitor differentiation. Cellular and Molecular Bioengineering, 10(5): 501-513.

  3. Davoudi S and Gilbert PM. (2017) Optimization of satellite cell culture through biomaterials. Methods in Molecular Biology, E. Perdiguero and D. Cornelison (ed.), New York, NY: Springer, 1556: 329-341.

  4. Gilbert PM* and Weaver VM*. (*Co-corresponding authors; 2016) Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Seminars in Cell and Developmental Biology, 67: 141-152.

  5. Morrissey-Scoot JD, Cheng R, Davoudi S, and Gilbert PM. (2016) Biomechanical origins of muscle stem cell signal transduction. J. Molecular Biology, 428(7): 1441-54.

  6. Cosgrove BD, Gilbert PM*, Porpiglia E, Mourkioti F, Lee SP, Corbel SY, Llewellyn ME, Delp SP and Blau HM*. (*Co-corresponding authors; 2014) Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. Nature Medicine, 20:255-64.

  7. Mouw JK, Yui Y, Damiano L, O Bainer R, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen Y-Y and Weaver VM. (2014) Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nature Medicine, 20:360-367.

  8. Gilbert PM and Blau HM. (2011) Engineering a stem cell house into a home. Stem cell research and therapy, 2(1): 1-9.

  9. Gilbert PM*, Havenstrite K*, Magnusson KEG, Sacco A, Leonardi N, Nguyen N, Kraft P, Thrun S, Lutolf M and Blau HM. (*Equal Contribution; 2010) Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science, 329(5995): 1078-81.

  10. Lutolf M, Gilbert PM and Blau HM (2009) Designing biomaterials to direct stem cell fate. Nature, 462:  433-441.

  11. Cosgrove BD, Sacco A, Gilbert PM, Blau HM (2009) A home away from home: Challenges and opportunities in engineering in vitro muscle satellite cell niches. Differentiation, 78(203):  185-94.

TISSUE ENGINEERING PUBLICATIONS:

  1. Bakooshli MA, Lippman ES, Mulcahy B, Iyer N, Nguyen CT, Tung K, Stewart BA, van den Dorpel H, Fuehrmann T, Shoichet MS, Bigot A, Pegoraro E, Ahn H, Ginsberg H, Zhen M, Ashton RS, and Gilbert PM. (2018). A three-dimensional culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction and disease modeling. BioRxiv, https://doi.org/10.1101/275545.

  2. Davoudi S, Chin C-Y, Cooke MC, Tam RY, Shoichet MS, and Gilbert PM. (2018) Muscle stem cell intramuscular delivery within hyaluronin methylcellulose improves engraftment efficiency and dispersion. Biomaterials, 173: 34-46.

  3. Nissar A, Martowirogo A, and Gilbert PM. (2016) Targeting the stem cell niche with regenerative biomaterials. Current Opinion in Solid State and Materials Science, 20(4): 180-192.

  4. Bakooshli MA and Gilbert PM. (2015) Muscling in on the third dimension. eLIFE, DOI: 10.7554/eLife.06430

  5. Sengupta D, Gilbert PM, Johnson KL, Blau HM and Heilshorn SC (2012) Protein-engineered biomaterials to generate human skeletal muscle mimics. Advanced Healthcare Materials, 1(6):785-789.

  6. Bakooshli, Mohsen Afshar, et al. “A Three-Dimensional Culture Model of Innervated Human Skeletal Muscle Enables Studies of the Adult Neuromuscular Junction and Disease Modeling.” 2018, doi:10.1101/275545.